Acid-base changes in haemodialysis.

Acid production and base balance in patients on chronic haemodialysis.

Acid generation and elimination processes were compared with total base (bicarbonate plus metabolizable anions) turnover in 18 anuric patients undergoing post-dilutional haemofiltration. The study was conducted during the second haemodialysis session of the week by means of a whole-body base balance technique. The results showed that the mean rates of base loss and base gain during dialysis did...

Changes in the acid-base equilibrium in essential hypertension.

In a study of a group of hospitalized patients in whom there was no reason to suspect a disturbed acid-base balance, it was found that a few patients had low blood pH values. The only factor in common to these patients with the low pH values was that all had essential hypertension. It has been demonstrated in human subjects that experimental hypertension can be produced with desoxycorticosteron...

Acid-base changes after cardiorespiratory arrest in the dog.

1. To assess the non-respiratory acid-base disturbance which results from cardiorespiratory arrest experiments were performed on anaesthetized dogs, and circulatory arrest was established either by inducing ventricular fibrillation or by complete occlusion of the great veins. 2. In the first series of experiments (group A) the period of cardiorespiratory arrest was limited to 2.0-3.5 min. It wa...

Contractility in isolated mammalian heart muscle after acid-base changes.

Changes in fetal acid base status during intravascular transfusion.

Umbilical venous pH, PCO2, PO2, and base excess was measured immediately before and after 72 intravascular transfusions in 34 fetuses with erythroblastosis fetalis. In 67 uncomplicated transfusions, infused adult blood led to a mean (95% confidence intervals) fall in pH (0.037, CI 0.029 to 0.044) and base excess (2.03, CI 1.61 to 2.45) and a mean rise in PCO2 (0.24 kPa, CI 0.13 to 0.35). These ...